Abcore has built an entire platform for nanobody and single domain antibody discovery. Our process is based on phage display and using either naïve phage libraries or immunized phage libraries for nanobody discovery.
Immunized Antibody Phage Libraries:
- Custom Llama Nanobody Discovery
- Custom Alpaca Nanobody Discovery
Naïve Antibody Phage Libraries:
- Naïve Llama Nanobody Phage Library
- Naïve Alpaca Nanobody Phage Library
- Naïve Camel Nanobody Phage Library
- Naïve Shark IgNAR Phage Library
- Naïve Rabbit ScFv Phage Library
The nanobody discovery process can be broken into phases, based on the goals of the single domain antibody project:
- Immunization
- PBMC Isolation
- cDNA generation
- Phage Library Construction
- Phage Library Panning
- Screening for Positive Clones
- Production of Purified Nanobodies
- Other CRO Services (Humanization, Functional Assays, Expression Vector changes, etc.)